Professor Charalambos Antoniades

MD, PhD, FESC


Profile

Professor Antoniades Charis is a full Professor of Cardiovascular Medicine at the University of Oxford, and a Consultant Cardiologist in Oxford University Hospitals. He graduated Medicine in Athens Medical School a with hons (top 3%) in 2000. He was awarded his PhD title with hons on the genetics of premature myocardial infarction, and he won multiple prestigious international Young Investigator award competitions. He has published  250 scientific papers and in 2016 he received the outstanding achievement award of the European Society of Cardiology. He is also deputy editor of Cardiovascular Research, editor of British Journal of Pharmacology and associate editor of other journals. He is board member of the British Atherosclerosis Society and one of the founders of the ESC Scientists of Tomorrow.

Prof Antoniades is particularly interested in the control of high blood pressure, and runs a Hypertension clinic at the Oxford University Hospitals. He also has SCCT accreditation and directs the Oxford Academic Cardiovascular CT Programme. He has recently discovered a new method that predicts future heart attacks by analysing coronary CT angiograms.

Prof Antoniades is founder and Chief Scientific Officer of Caristo Diagnostics, a university of Oxford spinout company commercialising novel CT-derived biomarkers for cardiovascular risk prediction. 


Clinics

  • Ad-Hoc

Locations

Current posts

  • Consultant cardiologist Roles: Hypertension service at the JR Hospital
  • List of Coronary Computed Tomography angiography at the JR hospital

Interests

  • Hypertension in obesity and other causes of resistant hypertension.
  • Advanced interpretation of coronary computed tomography angiography using novel tools that predict future heart attacks



Member of

  • Fellow of the European Society of Cardiology
  • Member of the Society of Cardiovascular Computed Tomography
  • Member of the British Atherosclerosis Society

Research

Prof Antoniades direct the Oxford Translational Cardiovascular Research group, and he is the Chief Investigator in many large platform studies such as the Oxford Heart Vessels and Fat (oxHVF) cohort and others. His research programme is focused on studying the interactions between fat and the cardiovascular system, aiming to understand how obesity and diabetes cause heart diseases.

He also directs the Oxford Academic Cardiovascular CT Programme, and he has recently discovered a new method, called Fat Attenuation Indexing (see Reuters report on FAI ), which enables early prediction of cardiovascular risk by analysing the appearances of the fat surrounding the heart vessels, from common coronary CT angiography images. This method was described in Science Transl Med 2017, and was further validated in a large cohort study that included 4000 patients, where it was found to predict fatal and non-fatal heart attacks (CRISP-CT study, Lancet 2018). This was highlighted in press (BBC NewsSky News , London Times , The Independent , New York Times, Yahoo News , The Guardian  and others.


Declaration

Professor Charalambos Antoniades does not hold a share or financial interest in this hospital, another Nuffield Health hospital or the company.

Professor Charalambos Antoniades does not have a share or financial interest in equipment used at this hospital or another Nuffield Health hospital.

Professor Charalambos Antoniades does not hold any paid advisory role(s) at this hospital or on behalf of Nuffield Health.