When the components that make up bile get out of balance gallstones can form. Gallstones are frequently not a problem and go unnoticed. However if a gallstone becomes trapped in the opening (duct) in your gall bladder it can cause severe abdominal pain lasting from one to five hours. 

Left untreated gallstone disease can cause persistent pain, yellowing of the eyes and skin (jaundice) and elevated body temperature. In severe cases gallstones can move to the pancreas causing pain and inflammation. 

Treatment for gallstones usually involves minimally invasive keyhole surgery (laparoscopic cholecystectomy).