Dr William Griffiths

Qualifications

MB BChir, MRCP, PhD

GMC number: 4070364

Practising since: 1993

Specialties

General (internal) Medicine, Gastroenterology

Sub-specialties: Hepatology

Consultation times

  • Monthly Tuesdays 14:00–16:00
  • Overview
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01223 370 922

About

Dr Griffiths was appointed in 2006 as a consultant hepatologist in a well-renowned tertiary liver centre and liver transplant unit, where he also trained.

Here he has a number of inpatient and outpatient duties; he runs, amongst others, a weekly new patient liver clinic and genetic liver clinic at Addenbrooke’s and regularly performs upper GI endoscopy, ERCP and endoscopic ultrasound.

Dr Griffiths has a particular interest in haemochromatosis and co-wrote the latest national guidelines. He also leads a UK special interest group on Wilson’s disease, served 10 years on the British Association Study of Liver (BASL) committee and is the National Lead for Hepatology training.

Typical hepatology areas:

  • Fatty liver disease
  • Alcohol-related liver damage
  • Hepatitis (A, B, C and autoimmune hepatitis)
  • Abnormal liver blood tests
  • Jaundice (yellow skin/eyes)
  • Cirrhosis and its complications
  • Liver cysts, tumours or liver cancer
  • Medication-related liver injury
  • Unexplained itching linked to bile problems
  • Gallbladder/bile duct disorders (e.g. primary biliary cholangitis).

Typical management and tests:

  • Interpret liver blood tests (ALT, AST, ALP, bilirubin, GGT)
  • Assess scans (ultrasound, FibroScan, MRI)
  • Diagnose why liver tests are abnormal
  • Manage long-term liver disease
  • Arrange liver biopsies
  • Adjust medications that affect the liver
  • Decide if someone needs referral to a transplant centre
  • Perform EUS (endoscopic ultra sound via OGD), liver biopsy and therapeutic ERCP.

Dr Griffiths secretary can be contacted here.

Other interests

  • Inherited liver disease
  • Biliary endoscopy
  • Liver transplantation.

Personal interests

Family, gardening, refereeing rugby and golf.

Treatments and tests offered by Dr William Griffiths at Nuffield Health

  • Diagnostic endoscopy
  • Liver function tests

Locations Dr William Griffiths works with

  •  

    4 Trumpington Road, Cambridge, CB2 8AF

    01223 370 922
    Overall rating
    Outstanding
     
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Related experience

Research

Recent principal author peer-reviewed

publications include:

1.      Griffiths WJ, Mayr R, McFarlane I, et al. Clinical presentation and molecular pathophysiology of autosomal dominant hemochromatosis caused by a novel ferroportin mutation. Hepatology 2010; 51:788-95
2.      Ambler GK……..Griffiths WJH. Orthotopic liver transplantation in an adult with cholesterol ester storage disease. JIMD reports 2013;8:41-6

3.      Cacciottolo TM……..Griffiths WJH. Pi*Z heterozygous alpha-1 antitrypsin states accelerate parenchymal but not biliary cirrhosis. European Journal of Gastro Hepatology 2014;26:412-7

4.      Azzu V……..Griffiths WJH. Liver disease predicts mortality in patients with X-linked immunodeficiency with hyper-IGM but can be prevented by early hematopoietic stem cell transplantation. J Allergy Clin Immunol 2018; 141:1405-8

5.      Fitzsimmons EJ…..Griffiths WJH. Diagnosis and therapy of genetic haemochromatosis (review and 2017 update). Br J Haematol 2018:181:293-303

6.      Bhuva M……Griffiths W. Sequence analaysis of exon 1 of the ferritin light chain (FTL) gene can reveal the rare disorder ‘hereditary hyperferritinaemia without cataracts’. Br J Haematol 2019;184:1037-1040

Memberships

  • Royal College of Physicians (Fellow)
  • British Association Study of Liver
  • American Association Study of Liver Disease
  • Gastroenterology Specialist Advisory Group

Other posts held

  • Cambridge University Hospitals NHS Foundation Trust

Insurers Dr William Griffiths works with

Dr William Griffiths works with the following private medical insurance providers:

  • Aviva Health
  • AXA Health
  • Bupa
  • Cigna
  • CS Healthcare
  • PHC
  • Vitality Health (Pru Health)
  • WPA

Declaration

Dr William Griffiths does not hold a share or financial interest in this hospital, another Nuffield Health hospital or the company.

Dr William Griffiths does not have a share or financial interest in equipment used at this hospital or another Nuffield Health hospital.

Dr William Griffiths does not hold any paid advisory role(s) at this hospital or on behalf of Nuffield Health.